ROR1 Literature

ROR1 Biology and Targeting

Jul 2014 Protein & Cell

ROR1, an Embryonic Protein with an Emerging Role in Cancer Biology

Dec 2014 Seminars in Cancer Biology

The Receptor Tyrosine Kinase ROR1--an Oncofetal Antigen for Targeted Cancer Therapy

Jul 2015 Expert Opinion on Therapeutic Targets

Receptor Tyrosine Kinase-Like Orphan Receptor 1: A Novel Target for Cancer Immunotherapy

ROR1 Expression in Hematologic Malignancies and Solid Tumors

Sep 2008 International Journal of Cancer

Ror1, a Cell Surface Receptor Tyrosine Kinase Is Expressed in Chronic Lymphocytic Leukemia and May Serve as a Putative Target for Therapy

Dec 2012 American Journal of Pathology

The Onco-Embryonic Antigen ROR1 Is Expressed by a Variety of Human Cancers

Apr 2013 Leukemia & Lymphoma

Orphan Receptor Tyrosine Kinases ROR1 and ROR2 in Hematological Malignancies

ROR1 Association with Tumor Aggressiveness and Adverse Outcomes

May 2012 PLoS One

ROR1 Is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth

Nov 2016 Scientific Reports

ROR1 is a Novel Prognostic Biomarker in Patients with Lung Adenocarcinoma

Anti-ROR1 Monoclonal Antibody Development

Jun 2015 Clinical Lymphoma, Myeloma & Leukemia

Pre-clinical Specificity and Safety of UC-961, a First-in-class Monoclonal Antibody Targeting ROR1

Jun 2018 Cell Stem Cell

Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia

VLS-101 Nonclinical Activity

Nov 2019 American Society of Hematology Meeting

VLS-101 Is a Novel Therapeutic Antibody-Drug Conjugate (ADC) Targeting Receptor Tyrosine Kinase-like Orphan Receptor 1 (ROR1) in Richter's Syndrome (RS)